منابع مشابه
Werner syndrome with psychosis.
Werner syndrome is a premature senility syndrome that manifests a variety of ageing symptoms starting from puberty. Approximately 10% of patients demonstrate low IQ. Reports regarding psychotic symptoms in Werner syndrome are rare. Here we report a case of Werner syndrome with flourishing psychotic symptoms. The patient was a 55-year-old unmarried woman. She was referred due to psychomotor exci...
متن کاملWerner Syndrome
Werner Syndrome (WS) is an autosomal recessive disease that leads to the premature manifestation of clinical symptoms associated with normal aging. Clinical symptoms include: short stature, graying/loss of hair, osteoporosis, cataracts, atherosclerosis, type II diabetes, hypogonadism, skin ulcers, reduced fertility, and high incidence of malignant neoplasms. They appear in one’s 20’s and 30’s, ...
متن کاملWerner Syndrome
Werner syndrome is a premature aging disease caused by the mutation in the WRN gene. The cloning and characterization of the WRN gene and its product allows investigators to study the disease and the human aging process at molecular level. This review summarizes the recent progresses on various aspects of the WRN research including functional analysis of the protein, interactive cloning, comple...
متن کاملWerner syndrome associated with renal involvement.
W syndrome (WS) is an autosomal recessive disease, which is characterized by premature aging, short stature, cataract, dermal atrophy and ulcers, turning white early on hairs, alopecia, vascular calcification, diabetes mellitus, and osteoporosis.1,2 Kidney involvement is rarely seen in WS.3,4 We report a case of WS associated with end stage renal failure without any risk factor. A 29-year-old m...
متن کاملAgeing in Werner syndrome.
Oxidative stress markers including pentosidine and homocysteine were examined comparing them with inflammation markers including highly sensitive C-reactive protein (hsCRP) and matrix metalloproteinase-9 (MMP-9) in serum from patients with Werner syndrome (WS) and healthy individuals. Elevation of serum pentosidine correlated significantly with normal aging in healthy individuals (p < 0.0004). ...
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ژورنال
عنوان ژورنال: Psychiatry and Clinical Neurosciences
سال: 2006
ISSN: 1323-1316,1440-1819
DOI: 10.1111/j.1440-1819.2006.01597.x